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Deubiquitinase USP35 stabilizes BRPF1 to activate mevalonate (MVA) metabolism during prostate tumorigenesis

The mutual interplay between epigenetic modifications and metabolic rewiring contributes to malignant features of prostate adenocarcinoma (PRAD). This study aimed to uncover the biological roles of deubiquitylase USP35 in PRAD and find effective epigenetic or metabolic targets. Bioinformatic tools o...

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Detalles Bibliográficos
Autores principales:	Lin, Guowen, Huang, Tianrun, Zhang, Xiaobo, Wang, Gangmin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9649703/ https://www.ncbi.nlm.nih.gov/pubmed/36357379 http://dx.doi.org/10.1038/s41420-022-01231-x

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