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Body weight-supported gait training for patients with spinal cord injury: a network meta-analysis of randomised controlled trials

Different body weight-supported gait-training strategies are available for improving ambulation in individuals with spinal cord injury (SCI). These include body weight-supported overground training (BWSOGT), body weight-supported treadmill training (BWSTT), and robot-assisted gait training (RAGT). W...

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Autores principales: Yang, Fu-An, Chen, Shih-Ching, Chiu, Jing-Fang, Shih, Ya-Chu, Liou, Tsan-Hon, Escorpizo, Reuben, Chen, Hung-Chou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9649733/
https://www.ncbi.nlm.nih.gov/pubmed/36357483
http://dx.doi.org/10.1038/s41598-022-23873-8
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author Yang, Fu-An
Chen, Shih-Ching
Chiu, Jing-Fang
Shih, Ya-Chu
Liou, Tsan-Hon
Escorpizo, Reuben
Chen, Hung-Chou
author_facet Yang, Fu-An
Chen, Shih-Ching
Chiu, Jing-Fang
Shih, Ya-Chu
Liou, Tsan-Hon
Escorpizo, Reuben
Chen, Hung-Chou
author_sort Yang, Fu-An
collection PubMed
description Different body weight-supported gait-training strategies are available for improving ambulation in individuals with spinal cord injury (SCI). These include body weight-supported overground training (BWSOGT), body weight-supported treadmill training (BWSTT), and robot-assisted gait training (RAGT). We conducted a network meta-analysis of randomised controlled trials (RCTs) to assess the effect and priority of each training protocol. We searched the PubMed, Cochrane Library, Scopus, and Embase databases from inception to 6 August 2022. The eligibility criteria were as follows: (1) being RCTs, (2) recruiting participants with SCI diagnosis and requiring gait training, (3) comparing different body weight-supported gait training strategies, and (4) involving ambulatory assessments. We conducted a network meta-analysis to compare different training strategies using the standard mean difference and its 95% credible interval. To rank the efficacy of training strategies, we used the P score as an indicator. Inconsistency in network meta-analysis was evaluated using loop-specific heterogeneity. We included 15 RCTs in this analysis. RAGT was had significantly more favourable performance than had the control intervention. The ranking probabilities indicated that the most effective approach was RAGT, followed by BWSOGT, BWSTT, and the control intervention. No significant inconsistency was noted between the results of the direct and indirect comparisons.
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spelling pubmed-96497332022-11-15 Body weight-supported gait training for patients with spinal cord injury: a network meta-analysis of randomised controlled trials Yang, Fu-An Chen, Shih-Ching Chiu, Jing-Fang Shih, Ya-Chu Liou, Tsan-Hon Escorpizo, Reuben Chen, Hung-Chou Sci Rep Article Different body weight-supported gait-training strategies are available for improving ambulation in individuals with spinal cord injury (SCI). These include body weight-supported overground training (BWSOGT), body weight-supported treadmill training (BWSTT), and robot-assisted gait training (RAGT). We conducted a network meta-analysis of randomised controlled trials (RCTs) to assess the effect and priority of each training protocol. We searched the PubMed, Cochrane Library, Scopus, and Embase databases from inception to 6 August 2022. The eligibility criteria were as follows: (1) being RCTs, (2) recruiting participants with SCI diagnosis and requiring gait training, (3) comparing different body weight-supported gait training strategies, and (4) involving ambulatory assessments. We conducted a network meta-analysis to compare different training strategies using the standard mean difference and its 95% credible interval. To rank the efficacy of training strategies, we used the P score as an indicator. Inconsistency in network meta-analysis was evaluated using loop-specific heterogeneity. We included 15 RCTs in this analysis. RAGT was had significantly more favourable performance than had the control intervention. The ranking probabilities indicated that the most effective approach was RAGT, followed by BWSOGT, BWSTT, and the control intervention. No significant inconsistency was noted between the results of the direct and indirect comparisons. Nature Publishing Group UK 2022-11-10 /pmc/articles/PMC9649733/ /pubmed/36357483 http://dx.doi.org/10.1038/s41598-022-23873-8 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Yang, Fu-An
Chen, Shih-Ching
Chiu, Jing-Fang
Shih, Ya-Chu
Liou, Tsan-Hon
Escorpizo, Reuben
Chen, Hung-Chou
Body weight-supported gait training for patients with spinal cord injury: a network meta-analysis of randomised controlled trials
title Body weight-supported gait training for patients with spinal cord injury: a network meta-analysis of randomised controlled trials
title_full Body weight-supported gait training for patients with spinal cord injury: a network meta-analysis of randomised controlled trials
title_fullStr Body weight-supported gait training for patients with spinal cord injury: a network meta-analysis of randomised controlled trials
title_full_unstemmed Body weight-supported gait training for patients with spinal cord injury: a network meta-analysis of randomised controlled trials
title_short Body weight-supported gait training for patients with spinal cord injury: a network meta-analysis of randomised controlled trials
title_sort body weight-supported gait training for patients with spinal cord injury: a network meta-analysis of randomised controlled trials
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9649733/
https://www.ncbi.nlm.nih.gov/pubmed/36357483
http://dx.doi.org/10.1038/s41598-022-23873-8
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