Cargando…

A new catalytic site functioning in antigen cleavage by H34 catalytic antibody light chain

The cleavage reactions of catalytic antibodies are mediated by a serine protease mechanism involving a catalytic triad composed of His, Ser, and Asp residues, which reside in the variable region. Recently, we discovered a catalytic antibody, H34 wild type (H34wt), that is capable of enzymatically cl...

Descripción completa

Detalles Bibliográficos
Autores principales: Hifumi, Emi, Nonaka, Tamami, Taguchi, Hiroaki, Uda, Taizo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9649737/
https://www.ncbi.nlm.nih.gov/pubmed/36357546
http://dx.doi.org/10.1038/s41598-022-23689-6