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A new catalytic site functioning in antigen cleavage by H34 catalytic antibody light chain
The cleavage reactions of catalytic antibodies are mediated by a serine protease mechanism involving a catalytic triad composed of His, Ser, and Asp residues, which reside in the variable region. Recently, we discovered a catalytic antibody, H34 wild type (H34wt), that is capable of enzymatically cl...
Autores principales: | Hifumi, Emi, Nonaka, Tamami, Taguchi, Hiroaki, Uda, Taizo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9649737/ https://www.ncbi.nlm.nih.gov/pubmed/36357546 http://dx.doi.org/10.1038/s41598-022-23689-6 |
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