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The 3D structure of lipidic fibrils of α-synuclein

α-synuclein misfolding and aggregation into fibrils is a common feature of α-synucleinopathies, such as Parkinson’s disease, in which α-synuclein fibrils are a characteristic hallmark of neuronal inclusions called Lewy bodies. Studies on the composition of Lewy bodies extracted postmortem from brain...

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Detalles Bibliográficos
Autores principales: Frieg, Benedikt, Antonschmidt, Leif, Dienemann, Christian, Geraets, James A., Najbauer, Eszter E., Matthes, Dirk, de Groot, Bert L., Andreas, Loren B., Becker, Stefan, Griesinger, Christian, Schröder, Gunnar F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9649780/
https://www.ncbi.nlm.nih.gov/pubmed/36357403
http://dx.doi.org/10.1038/s41467-022-34552-7

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