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The epigenetic state of IL-4-polarized macrophages enables inflammatory cistromic expansion and extended synergistic response to TLR ligands

Prior exposure to microenvironmental signals could fundamentally change the response of macrophages to subsequent stimuli. It is believed that T helper-2 (Th2)-cell-type cytokine interleukin-4 (IL-4) and Toll-like receptor (TLR) ligand-activated transcriptional programs mutually antagonize each othe...

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Detalles Bibliográficos
Autores principales:	Czimmerer, Zsolt, Halasz, Laszlo, Daniel, Bence, Varga, Zsofia, Bene, Krisztian, Domokos, Apolka, Hoeksema, Marten, Shen, Zeyang, Berger, Wilhelm K., Cseh, Timea, Jambrovics, Karoly, Kolostyak, Zsuzsanna, Fenyvesi, Ferenc, Varadi, Judit, Poliska, Szilard, Hajas, Gyorgy, Szatmari, Istvan, Glass, Christopher K., Bacsi, Attila, Nagy, Laszlo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9649892/ https://www.ncbi.nlm.nih.gov/pubmed/36323312 http://dx.doi.org/10.1016/j.immuni.2022.10.004

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