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IRE-1 endoribonuclease activity declines early in C. elegans adulthood and is not rescued by reduced reproduction
The proteome of a cell helps to define its functional specialization. Most proteins must be translated and properly folded to ensure their biological function, but with aging, animals lose their ability to maintain a correctly folded proteome. This leads to the accumulation of protein aggregates, de...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9649906/ https://www.ncbi.nlm.nih.gov/pubmed/36389122 http://dx.doi.org/10.3389/fragi.2022.1044556 |