Chip-based digital Polymerase Chain Reaction as quantitative technique for the detection of PIK3CA mutations in breast cancer patients

BACKGROUND: PIK3CA is a gene frequently mutated in breast cancer. With the FDA approval of alpelisib, the evaluation of PIK3CA for activating mutations is becoming routinely. Novel platforms for gene analysis as digital PCR (dPCR) are emerging as a potential replacement for the traditional Sanger se...

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Detalles Bibliográficos
Autores principales: Giannoni-Luza, Stefano, Acosta, Oscar, Murillo Carrasco, Alexis Germán, Danos, Pierina, Cotrina Concha, José Manuel, Guerra Miller, Henry, Pinto, Joseph A., Aguilar, Alfredo, Araujo, Jhajaira M., Fujita, Ricardo, Buleje, Jose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650006/
https://www.ncbi.nlm.nih.gov/pubmed/36387506
http://dx.doi.org/10.1016/j.heliyon.2022.e11396

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