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Evaluation of DNA adduct damage using G-quadruplex-based DNAzyme

Toxicity assessment is a major problem in pharmaceutical candidates and industry chemicals development. However, due to the lack of practical analytical methods for DNA adduct analysis, the safety evaluation of drug and industry chemicals was severely limited. Here, we develop a DNAzyme-based method...

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Detalles Bibliográficos
Autores principales: Xiao, Yi, Yi, Haomin, Zhu, Jingzhi, Chen, Suhua, Wang, Guofang, Liao, Yilong, Lei, Yuanyuan, Chen, Liyin, Zhang, Xingcai, Ye, Fangfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650010/
https://www.ncbi.nlm.nih.gov/pubmed/36406255
http://dx.doi.org/10.1016/j.bioactmat.2022.10.002