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Glycosylation network mapping and site-specific glycan maturation in vivo

Glycoprotein processing along a complex highly compartmentalized pathway is a hallmark of eukaryotic cells. We followed the kinetics of intracellular, site-specific glycan processing of a model protein with five distinct N-glycosylation sites and deduced a mathematical model of the secretory pathway...

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Detalles Bibliográficos
Autores principales: Losfeld, Marie-Estelle, Scibona, Ernesto, Lin, Chia-wei, Aebi, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650029/
https://www.ncbi.nlm.nih.gov/pubmed/36388954
http://dx.doi.org/10.1016/j.isci.2022.105417