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The RNA repair proteins RtcAB regulate transcription activator RtcR via its CRISPR-associated Rossmann fold domain

CRISPR-associated Rossmann fold (CARF) domain signaling underpins modulation of CRISPR-Cas nucleases; however, the RtcR CARF domain controls expression of two conserved RNA repair enzymes, cyclase RtcA and ligase RtcB. Here, we demonstrate that RtcAB are required for RtcR-dependent transcription act...

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Detalles Bibliográficos
Autores principales: Kotta-Loizou, Ioly, Giuliano, Maria Grazia, Jovanovic, Milija, Schaefer, Jorrit, Ye, Fuzhou, Zhang, Nan, Irakleidi, Danai Athina, Liu, Xiaojiao, Zhang, Xiaodong, Buck, Martin, Engl, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650030/
https://www.ncbi.nlm.nih.gov/pubmed/36388977
http://dx.doi.org/10.1016/j.isci.2022.105425

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