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I(KACh) is constitutively active via PKC epsilon in aging mediated atrial fibrillation

Atrial fibrillation (AF), the most common abnormal heart rhythm, is a major cause for stroke. Aging is a significant risk factor for AF; however, specific ionic pathways that can elucidate how aging leads to AF remain elusive. We used young and old wild-type and PKC epsilon- (PKCϵ) knockout mice, wh...

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Detalles Bibliográficos
Autores principales: Chang, Mengmeng, Gada, Kirin D., Chidipi, Bojjibabu, Tsalatsanis, Athanasios, Gibbons, Justin, Remily-Wood, Elizabeth, Logothetis, Diomedes E., Oberstaller, Jenna, Noujaim, Sami F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650037/
https://www.ncbi.nlm.nih.gov/pubmed/36388956
http://dx.doi.org/10.1016/j.isci.2022.105442