High-risk features of basilar artery atherosclerotic plaque

INTRODUCTION: High-resolution magnetic resonance imaging (HR-MRI) is used to characterize atherosclerotic plaque. The present study aimed to determine the high-risk features of the basilar artery (BA) atherosclerotic plaque. METHODS: Patients with advanced BA stenosis were screened. The features inc...

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Detalles Bibliográficos
Autores principales: Li, Shaojun, Wei, Jiana, Huang, Ruiyun, Li, Chenghao, Chen, Hongbing, Qiu, Zhihua, Jiang, Yongjun, Wu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650051/
https://www.ncbi.nlm.nih.gov/pubmed/36388175
http://dx.doi.org/10.3389/fneur.2022.1019036
Descripción
Sumario:INTRODUCTION: High-resolution magnetic resonance imaging (HR-MRI) is used to characterize atherosclerotic plaque. The present study aimed to determine the high-risk features of the basilar artery (BA) atherosclerotic plaque. METHODS: Patients with advanced BA stenosis were screened. The features including the ruptured fibrous cap (RFC), lipid core, intraplaque hemorrhage (IPH), plaque enhancement, and calcification were assessed by using high-resolution MRI. The relationship between the features and acute infarction was analyzed. RESULTS: From 1 June 2014 to 31 December 2018, a total of 143 patients with 76 new strokes were included. RFC was identified in 25% of symptomatic and 10.4% of asymptomatic patients. IPH was identified in 48.7% of symptomatic and 25.4% of asymptomatic patients. RFC (3.157, 95% CI 1.062 to 9.382, p = 0.039) and IPH (2.78, 95% CI 1.127 to 6.505, p = 0.026) were independent risk factors for acute infarction. CONCLUSION: Our study showed that RFC and IPH of BA plaque were independent risk factors for acute infarction.

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