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Mechanism of action and therapeutic use of bempedoic acid in atherosclerosis and metabolic syndrome

Bempedoic acid is a new cholesterol-lowering drug, which has recently received US FDA and EMA approval. This drug targets lipid and glucose metabolism as well as inflammation via downregulation of ATP-citrate lyase and upregulation of AMP-activated protein kinase (AMPK). The primary effect is the re...

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Detalles Bibliográficos
Autores principales:	Biolo, Gianni, Vinci, Pierandrea, Mangogna, Alessandro, Landolfo, Matteo, Schincariol, Paolo, Fiotti, Nicola, Mearelli, Filippo, Di Girolamo, Filippo Giorgio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650075/ https://www.ncbi.nlm.nih.gov/pubmed/36386319 http://dx.doi.org/10.3389/fcvm.2022.1028355

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