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Population pharmacokinetic analysis for dabigatran etexilate in Chinese patients with non-valvular atrial fibrillation

We aimed to develop a pharmacokinetic (PK) and pharmacodynamic (PD) model from healthy Chinese subjects and real-world non-valvular atrial fibrillation (NVAF) patients. We also investigated meaningful intrinsic and extrinsic factors and related biomarkers for bleeding events. We characterized the in...

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Detalles Bibliográficos
Autores principales:	Liu, Ya-ou, Xie, Qiu-fen, Liu, Zhi-yan, Wang, Zhe, Mu, Guang-yan, Zhang, Ya-tong, Zhao, Zi-nan, Yuan, Dong-dong, Guo, Li-ping, Wang, Na, Xiang, Jing, Song, Hong-tao, Jiang, Jie, Xiang, Qian, Cui, Yi-min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650305/ https://www.ncbi.nlm.nih.gov/pubmed/36386303 http://dx.doi.org/10.3389/fcvm.2022.998751

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