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APOE alleles modulate associations of plasma metabolites with variants from multiple genes on chromosome 19q13.3

The APOE ε2, ε3, and ε4 alleles differentially impact various complex diseases and traits. We examined whether these alleles modulated associations of 94 single-nucleotide polymorphisms (SNPs) harbored by 26 genes in 19q13.3 region with 217 plasma metabolites using Framingham Heart Study data. The a...

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Detalles Bibliográficos
Autores principales:	Nazarian, Alireza, Loiko, Elena, Yassine, Hussein N., Finch, Caleb E., Kulminski, Alexander M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650319/ https://www.ncbi.nlm.nih.gov/pubmed/36389057 http://dx.doi.org/10.3389/fnagi.2022.1023493

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