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Modulation of immune cell function, IDO expression and kynurenine production by the quorum sensor 2-heptyl-3-hydroxy-4-quinolone (PQS)

Many invasive micro-organisms produce ‘quorum sensor’ molecules which regulate colony expansion and may modulate host immune responses. We have examined the ability of Pseudomonas Quorum Sensor (PQS) to influence cytokine expression under conditions of inflammatory stress. The administration of PQS...

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Detalles Bibliográficos
Autores principales: Ogbechi, Joy, Huang, Yi-Shu, Clanchy, Felix I. L., Pantazi, Eirini, Topping, Louise M., Darlington, L. Gail, Williams, Richard O., Stone, Trevor W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650388/
https://www.ncbi.nlm.nih.gov/pubmed/36389710
http://dx.doi.org/10.3389/fimmu.2022.1001956