Advances in molecular biomarkers and liquid biopsy in gliomas

There have been significant strides toward understanding the molecular landscape of brain cancer. These advances have been focused on analyses of the tumor microenvironment and have recently expanded to include liquid biopsies to identify molecular biomarkers noninvasively. Moving from tissue to liq...

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Detalles Bibliográficos
Autores principales: Mathios, Dimitrios, Phallen, Jillian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Supplement Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650470/
https://www.ncbi.nlm.nih.gov/pubmed/36380861
http://dx.doi.org/10.1093/noajnl/vdac151
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author Mathios, Dimitrios
Phallen, Jillian
author_facet Mathios, Dimitrios
Phallen, Jillian
author_sort Mathios, Dimitrios
collection PubMed
description There have been significant strides toward understanding the molecular landscape of brain cancer. These advances have been focused on analyses of the tumor microenvironment and have recently expanded to include liquid biopsies to identify molecular biomarkers noninvasively. Moving from tissue to liquid-based analyses of molecular biomarkers has been challenging and currently, there are no approved noninvasive tests that are clinically useful. However, the emerging field of molecular liquid biopsy assay development in the neuro-oncology space has great potential to revolutionize the detection and monitoring of patients with brain cancer.
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spelling pubmed-96504702022-11-14 Advances in molecular biomarkers and liquid biopsy in gliomas Mathios, Dimitrios Phallen, Jillian Neurooncol Adv Supplement Articles There have been significant strides toward understanding the molecular landscape of brain cancer. These advances have been focused on analyses of the tumor microenvironment and have recently expanded to include liquid biopsies to identify molecular biomarkers noninvasively. Moving from tissue to liquid-based analyses of molecular biomarkers has been challenging and currently, there are no approved noninvasive tests that are clinically useful. However, the emerging field of molecular liquid biopsy assay development in the neuro-oncology space has great potential to revolutionize the detection and monitoring of patients with brain cancer. Oxford University Press 2022-11-11 /pmc/articles/PMC9650470/ /pubmed/36380861 http://dx.doi.org/10.1093/noajnl/vdac151 Text en © The Author(s) 2022. Published by Oxford University Press, the Society for Neuro-Oncology and the European Association of Neuro-Oncology. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Supplement Articles
Mathios, Dimitrios
Phallen, Jillian
Advances in molecular biomarkers and liquid biopsy in gliomas
title Advances in molecular biomarkers and liquid biopsy in gliomas
title_full Advances in molecular biomarkers and liquid biopsy in gliomas
title_fullStr Advances in molecular biomarkers and liquid biopsy in gliomas
title_full_unstemmed Advances in molecular biomarkers and liquid biopsy in gliomas
title_short Advances in molecular biomarkers and liquid biopsy in gliomas
title_sort advances in molecular biomarkers and liquid biopsy in gliomas
topic Supplement Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650470/
https://www.ncbi.nlm.nih.gov/pubmed/36380861
http://dx.doi.org/10.1093/noajnl/vdac151
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