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The impact of age-related hypomethylated DNA on immune signaling upon cellular demise
Aging is associated with decreased antigen-specific immunity and increased chronic inflammation. While DNA-sensing pathways might be involved, the molecular factors underlying these age-related aberrancies in immune signaling are unclear. Here, we consider the potential role of aging-induced hypomet...
Autores principales: | Urban, Lauren A., Trinh, Annie, Pearlman, Eric, Siryaporn, Albert, Downing, Timothy L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650629/ https://www.ncbi.nlm.nih.gov/pubmed/33994111 http://dx.doi.org/10.1016/j.it.2021.04.005 |
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