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Berberine: Ins and outs of a nature-made PCSK9 inhibitor

Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a secreted protein and a critical regulator of low-density lipoprotein-cholesterol (LDL-C) through inducing degradation of the LDL receptor (LDLR) within the hepatocyte lysosome. PCSK9 deficiency significantly improves the survival rate of car...

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Detalles Bibliográficos
Autores principales:	Ataei, Sarina, Kesharwani, Prashant, Sahebkar, Amirhossein
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Leibniz Research Centre for Working Environment and Human Factors 2022
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650693/ https://www.ncbi.nlm.nih.gov/pubmed/36381647 http://dx.doi.org/10.17179/excli2022-5234

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