Lack of APLP1 leads to subtle alterations in neuronal morphology but does not affect learning and memory

The amyloid precursor protein APP plays a crucial role in Alzheimer pathogenesis. Its physiological functions, however, are only beginning to be unraveled. APP belongs to a small gene family, including besides APP the closely related amyloid precursor-like proteins APLP1 and APLP2, that all constitu...

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Detalles Bibliográficos
Autores principales: Erdinger, Susanne, Amrein, Irmgard, Back, Michaela, Ludewig, Susann, Korte, Martin, von Engelhardt, Jakob, Wolfer, David P., Müller, Ulrike C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650715/
https://www.ncbi.nlm.nih.gov/pubmed/36385765
http://dx.doi.org/10.3389/fnmol.2022.1028836

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