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Cytomegalovirus infection reduced CD70 expression, signaling and expansion of viral specific memory CD8(+) T cells in healthy human adults
BACKGROUND: Cytomegalovirus (CMV) infection leads to effector memory CD8(+) T cell expansion and is associated with immune dysfunction in older adults. However, the molecular alterations of CMV-specific CD8(+) T cells in CMV infected healthy young and middle-aged adults has not been fully characteri...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650803/ https://www.ncbi.nlm.nih.gov/pubmed/36368988 http://dx.doi.org/10.1186/s12979-022-00307-7 |