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Cytomegalovirus infection reduced CD70 expression, signaling and expansion of viral specific memory CD8(+) T cells in healthy human adults

BACKGROUND: Cytomegalovirus (CMV) infection leads to effector memory CD8(+) T cell expansion and is associated with immune dysfunction in older adults. However, the molecular alterations of CMV-specific CD8(+) T cells in CMV infected healthy young and middle-aged adults has not been fully characteri...

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Detalles Bibliográficos
Autores principales: Lu, Jian, Chen, Guobing, Sorokina, Arina, Nguyen, Thomas, Wallace, Tonya, Nguyen, Cuong, Dunn, Christopher, Wang, Stephanie, Ellis, Samantha, Shi, Guixin, McKelvey, Julia, Sharov, Alexei, Liu, Yu-Tsueng, Schneck, Jonathan, Weng, Nan-ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650803/
https://www.ncbi.nlm.nih.gov/pubmed/36368988
http://dx.doi.org/10.1186/s12979-022-00307-7