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Social determinants of health in multiple sclerosis

Social determinants of health are the conditions in which people are born, grow, live, work and age. These circumstances are the non-medical factors that influence health outcomes. Evidence indicates that health behaviours, comorbidities and disease-modifying therapies all contribute to multiple scl...

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Autores principales: Dobson, Ruth, Rice, Dylan R., D’hooghe, Marie, Horne, Rachel, Learmonth, Yvonne, Mateen, Farrah J., Marck, Claudia H., Reyes, Saúl, Williams, Mitzi Joi, Giovannoni, Gavin, Ford, Helen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9651126/
https://www.ncbi.nlm.nih.gov/pubmed/36369488
http://dx.doi.org/10.1038/s41582-022-00735-5
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author Dobson, Ruth
Rice, Dylan R.
D’hooghe, Marie
Horne, Rachel
Learmonth, Yvonne
Mateen, Farrah J.
Marck, Claudia H.
Reyes, Saúl
Williams, Mitzi Joi
Giovannoni, Gavin
Ford, Helen L.
author_facet Dobson, Ruth
Rice, Dylan R.
D’hooghe, Marie
Horne, Rachel
Learmonth, Yvonne
Mateen, Farrah J.
Marck, Claudia H.
Reyes, Saúl
Williams, Mitzi Joi
Giovannoni, Gavin
Ford, Helen L.
author_sort Dobson, Ruth
collection PubMed
description Social determinants of health are the conditions in which people are born, grow, live, work and age. These circumstances are the non-medical factors that influence health outcomes. Evidence indicates that health behaviours, comorbidities and disease-modifying therapies all contribute to multiple sclerosis (MS) outcomes; however, our knowledge of the effects of social determinants — that is, the ‘risks of risks’ — on health has not yet changed our approach to MS. Assessing and addressing social determinants of health could fundamentally improve health and health care in MS; this approach has already been successful in improving outcomes in other chronic diseases. In this narrative Review, we identify and discuss the body of evidence supporting an effect of many social determinants of health, including racial background, employment and social support, on MS outcomes. It must be noted that many of the published studies were subject to bias, and screening tools and/or practical interventions that address these social determinants are, for the most part, lacking. The existing work does not fully explore the potential bidirectional and complex relationships between social determinants of health and MS, and the interpretation of findings is complicated by the interactions and intersections among many of the identified determinants. On the basis of the reviewed literature, we consider that, if effective interventions targeting social determinants of health were available, they could have substantial effects on MS outcomes. Therefore, funding for and focused design of studies to evaluate and address social determinants of health are urgently needed.
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spelling pubmed-96511262022-11-14 Social determinants of health in multiple sclerosis Dobson, Ruth Rice, Dylan R. D’hooghe, Marie Horne, Rachel Learmonth, Yvonne Mateen, Farrah J. Marck, Claudia H. Reyes, Saúl Williams, Mitzi Joi Giovannoni, Gavin Ford, Helen L. Nat Rev Neurol Review Article Social determinants of health are the conditions in which people are born, grow, live, work and age. These circumstances are the non-medical factors that influence health outcomes. Evidence indicates that health behaviours, comorbidities and disease-modifying therapies all contribute to multiple sclerosis (MS) outcomes; however, our knowledge of the effects of social determinants — that is, the ‘risks of risks’ — on health has not yet changed our approach to MS. Assessing and addressing social determinants of health could fundamentally improve health and health care in MS; this approach has already been successful in improving outcomes in other chronic diseases. In this narrative Review, we identify and discuss the body of evidence supporting an effect of many social determinants of health, including racial background, employment and social support, on MS outcomes. It must be noted that many of the published studies were subject to bias, and screening tools and/or practical interventions that address these social determinants are, for the most part, lacking. The existing work does not fully explore the potential bidirectional and complex relationships between social determinants of health and MS, and the interpretation of findings is complicated by the interactions and intersections among many of the identified determinants. On the basis of the reviewed literature, we consider that, if effective interventions targeting social determinants of health were available, they could have substantial effects on MS outcomes. Therefore, funding for and focused design of studies to evaluate and address social determinants of health are urgently needed. Nature Publishing Group UK 2022-11-11 2022 /pmc/articles/PMC9651126/ /pubmed/36369488 http://dx.doi.org/10.1038/s41582-022-00735-5 Text en © Springer Nature Limited 2022, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Review Article
Dobson, Ruth
Rice, Dylan R.
D’hooghe, Marie
Horne, Rachel
Learmonth, Yvonne
Mateen, Farrah J.
Marck, Claudia H.
Reyes, Saúl
Williams, Mitzi Joi
Giovannoni, Gavin
Ford, Helen L.
Social determinants of health in multiple sclerosis
title Social determinants of health in multiple sclerosis
title_full Social determinants of health in multiple sclerosis
title_fullStr Social determinants of health in multiple sclerosis
title_full_unstemmed Social determinants of health in multiple sclerosis
title_short Social determinants of health in multiple sclerosis
title_sort social determinants of health in multiple sclerosis
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9651126/
https://www.ncbi.nlm.nih.gov/pubmed/36369488
http://dx.doi.org/10.1038/s41582-022-00735-5
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