An interdisciplinary approach for the management and rehabilitation of a fibro-osseous neoplasm using platelet-rich gel and an implant-supported hybrid prosthesis

Fibro-osseous neoplasms such as central ossifying fibroma (COF) can lead to destructive expansile lesions involving the maxilla or the mandible. Management of such lesions usually involves surgical intervention in the form of enucleation or resection. Platelet-rich gel (PRG) has been known to expedite bone regeneration due to its osteoconductive property. PRG initiates a greater and faster initial cellular response in comparison to platelet-rich plasma and has better handling characteristics. The challenge in rehabilitation often occurs due to the size of the osseous defects postsurgery. Fixed prosthodontic rehabilitation with endosteal implants is a viable treatment approach in such cases, improving the oral health quality of life and masticatory efficiency, when compared to a removable partial denture. This case report describes the management of an extensive lesion of COF using PRG and rehabilitation with a screw-retained, implant-supported hybrid prosthesis.