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Solitary fibrous tumor of the masticator space – Report of a rare case
The solitary fibrous tumor (SFT) is a potentially malignant spindle cell neoplasm of the mesenchymal origin that was originally described as a thoracic lesion originating from the pleural tissue. Recently, numerous extrapleural sites of origin have been described, also affecting the head and neck re...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9651244/ https://www.ncbi.nlm.nih.gov/pubmed/36393946 http://dx.doi.org/10.4103/njms.NJMS_117_20 |
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author | Patil, V. Shruthi Vidya, Konduru Paul, S. Arun Tirkey, Amit Jiwan |
author_facet | Patil, V. Shruthi Vidya, Konduru Paul, S. Arun Tirkey, Amit Jiwan |
author_sort | Patil, V. Shruthi |
collection | PubMed |
description | The solitary fibrous tumor (SFT) is a potentially malignant spindle cell neoplasm of the mesenchymal origin that was originally described as a thoracic lesion originating from the pleural tissue. Recently, numerous extrapleural sites of origin have been described, also affecting the head and neck region. SFTs are benign in most cases, but 10%–15% of extrapleural SFTs show malignant behavior in the form of recurrent or metastatic disease. We present the case of a 25-year-old female who presented with an asymptomatic left-sided facial swelling of over three years. She had a diffuse swelling in the left preauricular region, extending to the temporal region deep to the zygomatic arch. On magnetic resonance imaging, the vascular lobulated mass occupied the masticator space, infratemporal fossa, and parapharyngeal space, eroding the mandible. An ultrasound-guided fine-needle aspiration cytology was suggestive of SFT, positive for signal transducer and activator of transcription 6 and negative for TLE1. After preoperative embolization, the tumor was excised through a midline lip split approach with posterior segmental mandibulectomy and reconstruction with a titanium plate. Histopathological report was consistent with SFT. Due to high-risk features, she was advised adjuvant radiation therapy. SFTs of the head and neck are exceedingly rare and those with aggressive behavior even more so. To our knowledge, this is the only case of SFT arising in the masticator space. Diagnosis is often difficult and not definitive without immunohistochemistry. In most cases, complete surgical excision is the only treatment necessary. Regardless, all patients require close clinical follow-up for several years. |
format | Online Article Text |
id | pubmed-9651244 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-96512442022-11-15 Solitary fibrous tumor of the masticator space – Report of a rare case Patil, V. Shruthi Vidya, Konduru Paul, S. Arun Tirkey, Amit Jiwan Natl J Maxillofac Surg Case Report The solitary fibrous tumor (SFT) is a potentially malignant spindle cell neoplasm of the mesenchymal origin that was originally described as a thoracic lesion originating from the pleural tissue. Recently, numerous extrapleural sites of origin have been described, also affecting the head and neck region. SFTs are benign in most cases, but 10%–15% of extrapleural SFTs show malignant behavior in the form of recurrent or metastatic disease. We present the case of a 25-year-old female who presented with an asymptomatic left-sided facial swelling of over three years. She had a diffuse swelling in the left preauricular region, extending to the temporal region deep to the zygomatic arch. On magnetic resonance imaging, the vascular lobulated mass occupied the masticator space, infratemporal fossa, and parapharyngeal space, eroding the mandible. An ultrasound-guided fine-needle aspiration cytology was suggestive of SFT, positive for signal transducer and activator of transcription 6 and negative for TLE1. After preoperative embolization, the tumor was excised through a midline lip split approach with posterior segmental mandibulectomy and reconstruction with a titanium plate. Histopathological report was consistent with SFT. Due to high-risk features, she was advised adjuvant radiation therapy. SFTs of the head and neck are exceedingly rare and those with aggressive behavior even more so. To our knowledge, this is the only case of SFT arising in the masticator space. Diagnosis is often difficult and not definitive without immunohistochemistry. In most cases, complete surgical excision is the only treatment necessary. Regardless, all patients require close clinical follow-up for several years. Wolters Kluwer - Medknow 2022-08 2022-08-20 /pmc/articles/PMC9651244/ /pubmed/36393946 http://dx.doi.org/10.4103/njms.NJMS_117_20 Text en Copyright: © 2022 National Journal of Maxillofacial Surgery https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Patil, V. Shruthi Vidya, Konduru Paul, S. Arun Tirkey, Amit Jiwan Solitary fibrous tumor of the masticator space – Report of a rare case |
title | Solitary fibrous tumor of the masticator space – Report of a rare case |
title_full | Solitary fibrous tumor of the masticator space – Report of a rare case |
title_fullStr | Solitary fibrous tumor of the masticator space – Report of a rare case |
title_full_unstemmed | Solitary fibrous tumor of the masticator space – Report of a rare case |
title_short | Solitary fibrous tumor of the masticator space – Report of a rare case |
title_sort | solitary fibrous tumor of the masticator space – report of a rare case |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9651244/ https://www.ncbi.nlm.nih.gov/pubmed/36393946 http://dx.doi.org/10.4103/njms.NJMS_117_20 |
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