Cargando…

An estimate assay for low-level exposure to ionizing radiation based on mass spectrometry quantification of γ-H2AX in human peripheral blood lymphocytes

Exposure to environmental ionizing radiation (IR) is ubiquitous, and large-dose exposure to IR is known to cause DNA damage and genotoxicity which is associated with an increased risk of cancer. Whether such detrimental effects are caused by exposure to low-dose IR is still debated. Therefore, rapid...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Hongling, Qu, Minmin, Li, Yuchen, Wen, Ke, Xu, Hua, Song, Man, Xie, Dafei, Ao, Xingkun, Gong, Yihao, Sui, Li, Guan, Hua, Zhou, Pingkun, Xie, Jianwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Public Health
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9651621/ https://www.ncbi.nlm.nih.gov/pubmed/36388350 http://dx.doi.org/10.3389/fpubh.2022.1031743

Ejemplares similares

Expression of γH2AX in various gastric pathologies and its association with Helicobacter pylori infection
por: XIE, CHUAN, et al.
Publicado: (2014)

Genome-wide multi-parametric analysis of H2AX or γH2AX distributions during ionizing radiation-induced DNA damage response
por: Natale, Francesco, et al.
Publicado: (2013)

Drug Discovery Targeting Post-Translational Modifications in Response to DNA Damages Induced by Space Radiation
por: Xie, Dafei, et al.
Publicado: (2023)

Study on γH2AX Expression of Lymphocytes as a Biomarker In Radiation Biodosimetry
por: Pan, Yan, et al.
Publicado: (2016)

Differences in the Establishment of Gut Microbiota and Metabolome Characteristics Between Balb/c and C57BL/6J Mice After Proton Irradiation
por: Li, Yuchen, et al.
Publicado: (2022)

Irradiation Activates MZF1 to Inhibit miR-541-5p Expression and Promote Epithelial-Mesenchymal Transition (EMT) in Radiation-Induced Pulmonary Fibrosis (RIPF) by Upregulating Slug
por: Liang, Xinxin, et al.
Publicado: (2021)

Low dose ionizing radiation strongly stimulates insertional mutagenesis in a γH2AX dependent manner
por: Zelensky, Alex N., et al.
Publicado: (2020)

Detection and quantification of γ-H2AX using a dissociation enhanced lanthanide fluorescence immunoassay
por: Noubissi, Felicite K., et al.
Publicado: (2021)

Genome Instability and γH2AX
por: Georgoulis, Anastasios, et al.
Publicado: (2017)

A statistical framework for radiation dose estimation with uncertainty quantification from the γ-H2AX assay
por: Einbeck, Jochen, et al.
Publicado: (2018)

BCLAF1 is a radiation-induced H2AX-interacting partner involved in γH2AX-mediated regulation of apoptosis and DNA repair
por: Lee, Y Y, et al.
Publicado: (2012)

Factors to Consider for the Correct Use of γH2AX in the Evaluation of DNA Double-Strand Breaks Damage Caused by Ionizing Radiation
por: Valente, Davide, et al.
Publicado: (2022)

Cytosolic Release of Mitochondrial DNA and Associated cGAS Signaling Mediates Radiation-Induced Hematopoietic Injury of Mice
por: Guan, Hua, et al.
Publicado: (2023)

γH2AX spreading linked to homology search
por: Renkawitz, Jörg, et al.
Publicado: (2013)

γ-H2AX Kinetic Profile in Mouse Lymphocytes Exposed to the Internal Emitters Cesium-137 and Strontium-90
por: Turner, Helen C., et al.
Publicado: (2015)

Accurate quantification of creatinine in serum by coupling a measurement standard to extractive electrospray ionization mass spectrometry
por: Huang, Keke, et al.
Publicado: (2016)

A Biomarker Panel of Radiation-Upregulated miRNA as Signature for Ionizing Radiation Exposure
por: Song, Man, et al.
Publicado: (2020)

Critical role of lysine 134 methylation on histone H2AX for γ-H2AX production and DNA repair
por: Sone, Kenbun, et al.
Publicado: (2014)

The Phosphorylated Form of the Histone H2AX (γH2AX) in the Brain from Embryonic Life to Old Age
por: Merighi, Adalberto, et al.
Publicado: (2021)

Deficiency of salt‐inducible kinase 2 (SIK2) promotes immune injury by inhibiting the maturation of lymphocytes
por: Zhu, Jiaojiao, et al.
Publicado: (2023)

Comprehensive Quantification of Triacylglycerols in Soybean Seeds by Electrospray Ionization Mass Spectrometry with Multiple Neutral Loss Scans
por: Li, Maoyin, et al.
Publicado: (2014)

Calibration of the γ-H2AX DNA Double Strand Break Focus Assay for Internal Radiation Exposure of Blood Lymphocytes
por: Eberlein, Uta, et al.
Publicado: (2015)

Heterochromatin is refractory to γ-H2AX modification in yeast and mammals
por: Kim, Jung-Ae, et al.
Publicado: (2007)

Endogenous DNA breaks: γH2AX and the role of telomeres
por: Olive, Peggy L.
Publicado: (2009)

Generation of an alpaca-derived nanobody recognizing γ-H2AX
por: Rajan, Malini, et al.
Publicado: (2015)

Regulation of host factor γ-H2AX level and location by enterovirus A71 for viral replication
por: Yu, Jinghua, et al.
Publicado: (2022)

Fast quantification of fluoroquinolones in environmental water samples using molecularly imprinted polymers coupled with internal extractive electrospray ionization mass spectrometry
por: Kou, Wei, et al.
Publicado: (2018)

Reliability of a Fully Automated Interpretation of γ-H2AX Foci in Lymphocytes of Moderately Trained Subjects under Resting Conditions
por: Heydenreich, Juliane, et al.
Publicado: (2014)

Genome-wide profiles of H2AX and γ-H2AX differentiate endogenous and exogenous DNA damage hotspots in human cells
por: Seo, Jungmin, et al.
Publicado: (2012)

Low level phosphorylation of histone H2AX on serine 139 (γH2AX) is not associated with DNA double-strand breaks
por: Rybak, Paulina, et al.
Publicado: (2016)

Expression of the γ-phosphorylated histone H2AX in gastric carcinoma and gastric precancerous lesions
por: GUO, ZHONG, et al.
Publicado: (2015)

Residual γH2AX foci as an indication of lethal DNA lesions
por: Banáth, Judit P, et al.
Publicado: (2010)

Correlation of dynamic changes in γ-H2AX expression in peripheral blood lymphocytes from head and neck cancer patients with radiation-induced oral mucositis
por: Li, Ping, et al.
Publicado: (2013)

Accuracy of matrix-assisted LASER desorption ionization–time of flight mass spectrometry for identification of Candida
por: Xie, Tian-Ao, et al.
Publicado: (2019)

Editorial: Epigenetic and Related Signaling Pathways in Response to Ionizing Radiation and Nano-Particles
por: Huang, Ruixue, et al.
Publicado: (2022)

"Magic" Ionization Mass Spectrometry
por: Trimpin, Sarah
Publicado: (2015)

Controlled bile acid exposure to oesophageal mucosa causes up-regulation of nuclear γ-H2AX possibly via iNOS induction
por: Jiang, Bo, et al.
Publicado: (2016)

Accurate Quantification of Lipid Species by Electrospray Ionization Mass Spectrometry — Meets a Key Challenge in Lipidomics
por: Yang, Kui, et al.
Publicado: (2011)

Quantification of Signaling Lipids by Nano-Electrospray Ionization Tandem Mass Spectrometry (Nano-ESI MS/MS)
por: Haag, Mathias, et al.
Publicado: (2012)

Metabolic Effects of Clenbuterol and Salbutamol on Pork Meat Studied Using Internal Extractive Electrospray Ionization Mass Spectrometry
por: Lu, Haiyan, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_32pldr5vk4cg0sqsltm1b4iuv2