Differentiation and on axon-guidance chip culture of human pluripotent stem cell-derived peripheral cholinergic neurons for airway neurobiology studies

Airway cholinergic nerves play a key role in airway physiology and disease. In asthma and other diseases of the respiratory tract, airway cholinergic neurons undergo plasticity and contribute to airway hyperresponsiveness and mucus secretion. We currently lack human in vitro models for airway cholin...

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Detalles Bibliográficos
Autores principales: Goldsteen, P. A., Sabogal Guaqueta, A. M., Mulder, P. P. M. F. A., Bos, I. S. T., Eggens, M., Van der Koog, L., Soeiro, J. T., Halayko, A. J., Mathwig, K., Kistemaker, L. E. M., Verpoorte, E. M. J., Dolga, A. M., Gosens, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9651921/
https://www.ncbi.nlm.nih.gov/pubmed/36386177
http://dx.doi.org/10.3389/fphar.2022.991072

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