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Enhanced immunogenicity of Mycobacterium bovis BCG through CRISPRi mediated depletion of AftC

Mycobacterium tuberculosis causes the disease tuberculosis and affects a third of the world’s population. The recent COVID-19 pandemic exacerbated the situation with a projected 27% increase in tuberculosis related deaths. M. tuberculosis has an elaborate cell wall consisting of peptidoglycan, arabi...

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Detalles Bibliográficos
Autores principales:	Madduri, Bala T.S.A., Allen, Lauren, Taylor, Stephen C., Besra, Gurdyal S., Alderwick, Luke J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9651938/ https://www.ncbi.nlm.nih.gov/pubmed/36405350 http://dx.doi.org/10.1016/j.tcsw.2022.100088

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