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Antiviral function and viral antagonism of the rapidly evolving dynein activating adaptor NINL

Viruses interact with the intracellular transport machinery to promote viral replication. Such host–virus interactions can drive host gene adaptation, leaving signatures of pathogen-driven evolution in host genomes. Here, we leverage these genetic signatures to identify the dynein activating adaptor...

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Detalles Bibliográficos
Autores principales: Stevens, Donté Alexander, Beierschmitt, Christopher, Mahesula, Swetha, Corley, Miles R, Salogiannis, John, Tsu, Brian V, Cao, Bryant, Ryan, Andrew P, Hakozawki, Hiroyuki, Reck-Peterson, Samara L, Daugherty, Matthew D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9651953/
https://www.ncbi.nlm.nih.gov/pubmed/36222652
http://dx.doi.org/10.7554/eLife.81606