Multivalent S2-based vaccines provide broad protection against SARS-CoV-2 variants of concern and pangolin coronaviruses

BACKGROUND: The COVID-19 pandemic continues to cause morbidity and mortality worldwide. Most approved COVID-19 vaccines generate a neutralizing antibody response that primarily targets the highly variable receptor-binding domain (RBD) of the SARS-CoV-2 spike (S) protein. SARS-CoV-2 “variants of conc...

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Detalles Bibliográficos
Autores principales: Halfmann, Peter J., Frey, Steven J., Loeffler, Kathryn, Kuroda, Makoto, Maemura, Tadashi, Armbrust, Tammy, Yang, Jie E., Hou, Yixuan J., Baric, Ralph, Wright, Elizabeth R., Kawaoka, Yoshihiro, Kane, Ravi S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9651965/
https://www.ncbi.nlm.nih.gov/pubmed/36375316
http://dx.doi.org/10.1016/j.ebiom.2022.104341

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