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Mesangial Cell–Derived Exosomal miR-4455 Induces Podocyte Injury in IgA Nephropathy by Targeting ULK2

Growing evidence suggests that mesangial cells (MCs) play a crucial role in the pathogenesis of IgA nephropathy (IgAN) by secreting aIgA1. However, the mechanism by which MCs regulate podocyte injury remains unknown. This study demonstrated that MC-derived exosomes treated with aIgA1 induced podocyt...

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Detalles Bibliográficos
Autores principales:	Yu, Mengjie, Shen, Xiaogang, He, Wenfang, Zheng, Danna, He, Qiang, Jin, Juan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652064/ https://www.ncbi.nlm.nih.gov/pubmed/36388165 http://dx.doi.org/10.1155/2022/1740770

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