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Ultrasonically Enhanced ZD2767P–Carboxypeptidase G2 Deactivates Cisplatin-Resistant Human Lung Cancer Cells

The prodrug–enzyme regimen ZD2767P+CPG2 is limited by low efficacy. Here, ultrasound was used to modulate ZD2767P+CPG2 (i.e., ZD2767P+CPG2+US) against cisplatin-resistant human lung cancer cells. A549 and A549/DDP (resistant subline) cells received ZD2767P+CPG2 or ZD2767P+CPG2+US. Either ZD2767P+CPG...

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Detalles Bibliográficos
Autores principales:	Liu, Qianfen, Li, Xinya, Luo, Yuanyuan, Wang, Houmei, Zhang, Ying, Yu, Tinghe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652066/ https://www.ncbi.nlm.nih.gov/pubmed/36388164 http://dx.doi.org/10.1155/2022/9191233

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