Identification of the ultrahigh-risk subgroup in neuroblastoma cases through DNA methylation analysis and its treatment exploiting cancer metabolism

Neuroblastomas require novel therapies that are based on the exploitation of their biological mechanism. To address this need, we analyzed the DNA methylation and expression datasets of neuroblastomas, extracted a candidate gene characterizing the aggressive features, and conducted functional studie...

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Detalles Bibliográficos
Autores principales: Watanabe, Kentaro, Kimura, Shunsuke, Seki, Masafumi, Isobe, Tomoya, Kubota, Yasuo, Sekiguchi, Masahiro, Sato-Otsubo, Aiko, Hiwatari, Mitsuteru, Kato, Motohiro, Oka, Akira, Koh, Katsuyoshi, Sato, Yusuke, Tanaka, Hiroko, Miyano, Satoru, Kawai, Tomoko, Hata, Kenichiro, Ueno, Hiroo, Nannya, Yasuhito, Suzuki, Hiromichi, Yoshida, Kenichi, Fujii, Yoichi, Nagae, Genta, Aburatani, Hiroyuki, Ogawa, Seishi, Takita, Junko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652143/
https://www.ncbi.nlm.nih.gov/pubmed/36319669
http://dx.doi.org/10.1038/s41388-022-02489-2

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