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Intralesional TLR4 agonist treatment strengthens the organ defense against colonizing cancer cells in the brain

Brain metastasis in breast cancer remains difficult to treat and its incidence is increasing. Therefore, the development of new therapies is of utmost clinical relevance. Recently, toll-like receptor (TLR) 4 was correlated with IL6 expression and poor prognosis in 1 215 breast cancer primaries. In c...

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Detalles Bibliográficos
Autores principales:	Blazquez, Raquel, Chuang, Han-Ning, Wenske, Britta, Trigueros, Laura, Wlochowitz, Darius, Liguori, Renato, Ferrazzi, Fulvia, Regen, Tommy, Proescholdt, Martin A., Rohde, Veit, Riemenschneider, Markus J., Stadelmann, Christine, Bleckmann, Annalen, Beißbarth, Tim, van Rossum, Denise, Hanisch, Uwe K., Pukrop, Tobias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652147/ https://www.ncbi.nlm.nih.gov/pubmed/36224342 http://dx.doi.org/10.1038/s41388-022-02496-3

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