Evolving polarisation of infiltrating and alveolar macrophages in the lung during metastatic progression of melanoma suggests CCR1 as a therapeutic target

Metastatic tumour progression is facilitated by tumour associated macrophages (TAMs) that enforce pro-tumour mechanisms and suppress immunity. In pulmonary metastases, it is unclear whether TAMs comprise tissue resident or infiltrating, recruited macrophages; and the different expression patterns of...

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Detalles Bibliográficos
Autores principales: Tapmeier, Thomas T., Howell, Jake H., Zhao, Lei, Papiez, Bartlomiej W., Schnabel, Julia A., Muschel, Ruth J., Gal, Annamaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652148/
https://www.ncbi.nlm.nih.gov/pubmed/36241867
http://dx.doi.org/10.1038/s41388-022-02488-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652148/
https://www.ncbi.nlm.nih.gov/pubmed/36241867
http://dx.doi.org/10.1038/s41388-022-02488-3

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