Nutritional deficiency in an intestine-on-a-chip recapitulates injury hallmarks associated with environmental enteric dysfunction

Environmental enteric dysfunction (EED)—a chronic inflammatory condition of the intestine—is characterized by villus blunting, compromised intestinal barrier function and reduced nutrient absorption. Here we show that essential genotypic and phenotypic features of EED-associated intestinal injury ca...

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Detalles Bibliográficos
Autores principales: Bein, Amir, Fadel, Cicely W., Swenor, Ben, Cao, Wuji, Powers, Rani K., Camacho, Diogo M., Naziripour, Arash, Parsons, Andrew, LoGrande, Nina, Sharma, Sanjay, Kim, Seongmin, Jalili-Firoozinezhad, Sasan, Grant, Jennifer, Breault, David T., Iqbal, Junaid, Ali, Asad, Denson, Lee A., Moore, Sean R., Prantil-Baun, Rachelle, Goyal, Girija, Ingber, Donald E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652151/
https://www.ncbi.nlm.nih.gov/pubmed/35739419
http://dx.doi.org/10.1038/s41551-022-00899-x

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