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K-80003 Inhibition of Macrophage Apoptosis and Necrotic Core Development in Atherosclerotic Vulnerable Plaques

PURPOSE: Macrophage apoptosis coupled with a defective phagocytic clearance of the apoptotic cells promotes plaque necrosis in advanced atherosclerosis, which causes acute atherothrombotic vascular disease. Nonsteroidal anti-inflammatory drug sulindac derivative K-80003 treatment was previously repo...

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Detalles Bibliográficos
Autores principales:	Wang, Xiaolei, Sun, Zhe, Yuan, Ruosen, Zhang, Weifeng, Shen, Yejiao, Yin, Anwen, Li, Yanjie, Ji, Qingqi, Wang, Xia, Li, Yi, Zhang, Min, Pan, Xin, Shen, Linghong, He, Ben
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652240/ https://www.ncbi.nlm.nih.gov/pubmed/34410548 http://dx.doi.org/10.1007/s10557-021-07237-4

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