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Updated trabecular bone score accounting for the soft tissue thickness (TBS(TT)) demonstrated significantly improved bone microstructure with denosumab in the FREEDOM TBS post hoc analysis

SUMMARY: TBS algorithm has been updated to account for regional soft tissue noise. In postmenopausal women with osteoporosis, denosumab improved tissue thickness–adjusted TBS vs placebo independently of bone mineral density over 3 years, with the magnitude of changes from baseline or placebo numeric...

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Detalles Bibliográficos
Autores principales: Hans, Didier, Shevroja, Enisa, McDermott, Michele, Huang, Shuang, Kim, Min, McClung, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer London 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652244/
https://www.ncbi.nlm.nih.gov/pubmed/36115888
http://dx.doi.org/10.1007/s00198-022-06549-x