Impaired mitochondrial oxidative metabolism in skeletal progenitor cells leads to musculoskeletal disintegration

Although skeletal progenitors provide a reservoir for bone-forming osteoblasts, the major energy source for their osteogenesis remains unclear. Here, we demonstrate a requirement for mitochondrial oxidative phosphorylation in the osteogenic commitment and differentiation of skeletal progenitors. Del...

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Detalles Bibliográficos
Autores principales: Lin, Chujiao, Yang, Qiyuan, Guo, Dongsheng, Xie, Jun, Yang, Yeon-Suk, Chaugule, Sachin, DeSouza, Ngoc, Oh, Won-Taek, Li, Rui, Chen, Zhihao, John, Aijaz A., Qiu, Qiang, Zhu, Lihua Julie, Greenblatt, Matthew B., Ghosh, Sankar, Li, Shaoguang, Gao, Guangping, Haynes, Cole, Emerson, Charles P., Shim, Jae-Hyuck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652319/
https://www.ncbi.nlm.nih.gov/pubmed/36369293
http://dx.doi.org/10.1038/s41467-022-34694-8

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