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dcHiC detects differential compartments across multiple Hi-C datasets

The compartmental organization of mammalian genomes and its changes play important roles in distinct biological processes. Here, we introduce dcHiC, which utilizes a multivariate distance measure to identify significant changes in compartmentalization among multiple contact maps. Evaluating dcHiC on...

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Detalles Bibliográficos
Autores principales: Chakraborty, Abhijit, Wang, Jeffrey G., Ay, Ferhat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652325/
https://www.ncbi.nlm.nih.gov/pubmed/36369226
http://dx.doi.org/10.1038/s41467-022-34626-6

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