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Cryo-EM structures of human m(6)A writer complexes

N(6)-methyladenosine (m(6)A) is the most abundant ribonucleotide modification among eukaryotic messenger RNAs. The m(6)A “writer” consists of the catalytic subunit m(6)A-METTL complex (MAC) and the regulatory subunit m(6)A-METTL-associated complex (MACOM), the latter being essential for enzymatic ac...

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Detalles Bibliográficos
Autores principales: Su, Shichen, Li, Shanshan, Deng, Ting, Gao, Minsong, Yin, Yue, Wu, Baixing, Peng, Chao, Liu, Jianzhao, Ma, Jinbiao, Zhang, Kaiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652331/
https://www.ncbi.nlm.nih.gov/pubmed/36167981
http://dx.doi.org/10.1038/s41422-022-00725-8

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