Stromal FOXF2 suppresses prostate cancer progression and metastasis by enhancing antitumor immunity

Cancer-associated fibroblasts (CAFs) mediate an immunosuppressive effect, but the underlying mechanism remains incompletely defined. Here we show that increasing prostatic stromal Foxf2 suppresses the growth and progression of both syngeneic and autochthonous mouse prostate cancer models in an immun...

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Detalles Bibliográficos
Autores principales: Jia, Deyong, Zhou, Zhicheng, Kwon, Oh-Joon, Zhang, Li, Wei, Xing, Zhang, Yiqun, Yi, Mingyang, Roudier, Martine P., Regier, Mary C., Dumpit, Ruth, Nelson, Peter S., Headley, Mark, True, Lawrence, Lin, Daniel W., Morrissey, Colm, Creighton, Chad J., Xin, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652358/
https://www.ncbi.nlm.nih.gov/pubmed/36369237
http://dx.doi.org/10.1038/s41467-022-34665-z

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