Cargando…
Programmable integrin and N-cadherin adhesive interactions modulate mechanosensing of mesenchymal stem cells by cofilin phosphorylation
During mesenchymal development, the sources of mechanical forces transduced by cells transition over time from predominantly cell-cell interactions to predominantly cell-extracellular matrix (ECM) interactions. Transduction of the associated mechanical signals is critical for development, but how th...
Autores principales: | Zhang, Zheng, Sha, Baoyong, Zhao, Lingzhu, Zhang, Huan, Feng, Jinteng, Zhang, Cheng, Sun, Lin, Luo, Meiqing, Gao, Bin, Guo, Hui, Wang, Zheng, Xu, Feng, Lu, Tian Jian, Genin, Guy M., Lin, Min |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652405/ https://www.ncbi.nlm.nih.gov/pubmed/36369425 http://dx.doi.org/10.1038/s41467-022-34424-0 |
Ejemplares similares
-
Nanoscale integrin cluster dynamics controls cellular mechanosensing via FAKY397 phosphorylation
por: Cheng, Bo, et al.
Publicado: (2020) -
Mechanics-driven nuclear localization of YAP can be reversed by N-cadherin ligation in mesenchymal stem cells
por: Zhang, Cheng, et al.
Publicado: (2021) -
N-Cadherin adhesive interactions modulate matrix mechanosensing and fate commitment of mesenchymal stem cells
por: Cosgrove, Brian D., et al.
Publicado: (2016) -
α-catenin, vinculin, and F-actin in strengthening E-cadherin cell–cell adhesions and mechanosensing
por: Dufour, Sylvie, et al.
Publicado: (2013) -
α-Catenin links integrin adhesions to F-actin to regulate ECM mechanosensing and rigidity dependence
por: Mukherjee, Abhishek, et al.
Publicado: (2022)