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The Health Gym: synthetic health-related datasets for the development of reinforcement learning algorithms

In recent years, the machine learning research community has benefited tremendously from the availability of openly accessible benchmark datasets. Clinical data are usually not openly available due to their confidential nature. This has hampered the development of reproducible and generalisable mach...

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Autores principales: Kuo, Nicholas I-Hsien, Polizzotto, Mark N., Finfer, Simon, Garcia, Federico, Sönnerborg, Anders, Zazzi, Maurizio, Böhm, Michael, Kaiser, Rolf, Jorm, Louisa, Barbieri, Sebastiano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652426/
https://www.ncbi.nlm.nih.gov/pubmed/36369205
http://dx.doi.org/10.1038/s41597-022-01784-7
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author Kuo, Nicholas I-Hsien
Polizzotto, Mark N.
Finfer, Simon
Garcia, Federico
Sönnerborg, Anders
Zazzi, Maurizio
Böhm, Michael
Kaiser, Rolf
Jorm, Louisa
Barbieri, Sebastiano
author_facet Kuo, Nicholas I-Hsien
Polizzotto, Mark N.
Finfer, Simon
Garcia, Federico
Sönnerborg, Anders
Zazzi, Maurizio
Böhm, Michael
Kaiser, Rolf
Jorm, Louisa
Barbieri, Sebastiano
author_sort Kuo, Nicholas I-Hsien
collection PubMed
description In recent years, the machine learning research community has benefited tremendously from the availability of openly accessible benchmark datasets. Clinical data are usually not openly available due to their confidential nature. This has hampered the development of reproducible and generalisable machine learning applications in health care. Here we introduce the Health Gym - a growing collection of highly realistic synthetic medical datasets that can be freely accessed to prototype, evaluate, and compare machine learning algorithms, with a specific focus on reinforcement learning. The three synthetic datasets described in this paper present patient cohorts with acute hypotension and sepsis in the intensive care unit, and people with human immunodeficiency virus (HIV) receiving antiretroviral therapy. The datasets were created using a novel generative adversarial network (GAN). The distributions of variables, and correlations between variables and trends in variables over time in the synthetic datasets mirror those in the real datasets. Furthermore, the risk of sensitive information disclosure associated with the public distribution of the synthetic datasets is estimated to be very low.
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spelling pubmed-96524262022-11-15 The Health Gym: synthetic health-related datasets for the development of reinforcement learning algorithms Kuo, Nicholas I-Hsien Polizzotto, Mark N. Finfer, Simon Garcia, Federico Sönnerborg, Anders Zazzi, Maurizio Böhm, Michael Kaiser, Rolf Jorm, Louisa Barbieri, Sebastiano Sci Data Data Descriptor In recent years, the machine learning research community has benefited tremendously from the availability of openly accessible benchmark datasets. Clinical data are usually not openly available due to their confidential nature. This has hampered the development of reproducible and generalisable machine learning applications in health care. Here we introduce the Health Gym - a growing collection of highly realistic synthetic medical datasets that can be freely accessed to prototype, evaluate, and compare machine learning algorithms, with a specific focus on reinforcement learning. The three synthetic datasets described in this paper present patient cohorts with acute hypotension and sepsis in the intensive care unit, and people with human immunodeficiency virus (HIV) receiving antiretroviral therapy. The datasets were created using a novel generative adversarial network (GAN). The distributions of variables, and correlations between variables and trends in variables over time in the synthetic datasets mirror those in the real datasets. Furthermore, the risk of sensitive information disclosure associated with the public distribution of the synthetic datasets is estimated to be very low. Nature Publishing Group UK 2022-11-11 /pmc/articles/PMC9652426/ /pubmed/36369205 http://dx.doi.org/10.1038/s41597-022-01784-7 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Data Descriptor
Kuo, Nicholas I-Hsien
Polizzotto, Mark N.
Finfer, Simon
Garcia, Federico
Sönnerborg, Anders
Zazzi, Maurizio
Böhm, Michael
Kaiser, Rolf
Jorm, Louisa
Barbieri, Sebastiano
The Health Gym: synthetic health-related datasets for the development of reinforcement learning algorithms
title The Health Gym: synthetic health-related datasets for the development of reinforcement learning algorithms
title_full The Health Gym: synthetic health-related datasets for the development of reinforcement learning algorithms
title_fullStr The Health Gym: synthetic health-related datasets for the development of reinforcement learning algorithms
title_full_unstemmed The Health Gym: synthetic health-related datasets for the development of reinforcement learning algorithms
title_short The Health Gym: synthetic health-related datasets for the development of reinforcement learning algorithms
title_sort health gym: synthetic health-related datasets for the development of reinforcement learning algorithms
topic Data Descriptor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652426/
https://www.ncbi.nlm.nih.gov/pubmed/36369205
http://dx.doi.org/10.1038/s41597-022-01784-7
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