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Optogenetic restoration of high sensitivity vision with bReaChES, a red-shifted channelrhodopsin

The common final pathway to blindness in many forms of retinal degeneration is the death of the light-sensitive primary retinal neurons. However, the normally light-insensitive second- and third-order neurons persist optogenetic gene therapy aims to restore sight by rendering such neurons light-sens...

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Detalles Bibliográficos
Autores principales:	Too, Lay Khoon, Shen, Weiyong, Protti, Dario A., Sawatari, Atomu, A. Black, Dylan, Leamey, Catherine A., Y. Huang, Jin, Lee, So-Ra, E. Mathai, Ashish, Lisowski, Leszek, Y. Lin, John, C. Gillies, Mark, Simunovic, Matthew P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652428/ https://www.ncbi.nlm.nih.gov/pubmed/36369267 http://dx.doi.org/10.1038/s41598-022-23572-4

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