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An evaluation of a supratherapeutic dose of inclisiran on cardiac repolarization in healthy volunteers: A phase I, randomized study

Inclisiran is a small interfering RNA molecule that has been shown to provide an effective and sustained reduction in low‐density lipoprotein cholesterol levels. This study aimed to determine whether a supratherapeutic dose of inclisiran affects cardiac repolarization and conduction in healthy volun...

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Detalles Bibliográficos
Autores principales: Kallend, David, Mason, Jay, Smith, Patrick F., Koren, Michael J., Stoekenbroek, Robert, He, YanLing, Wijngaard, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652432/
https://www.ncbi.nlm.nih.gov/pubmed/36196601
http://dx.doi.org/10.1111/cts.13391

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