Cargando…

Glucocorticoids mediate transcriptome‐wide alternative polyadenylation: Potential mechanistic and clinical implications

Alternative polyadenylation (APA) is a common genetic regulatory mechanism that generates distinct 3′ ends for RNA transcripts. Changes in APA have been associated with multiple biological processes and disease phenotypes. However, the role of hormones and their drug analogs in APA remains largely u...

Descripción completa

Detalles Bibliográficos
Autores principales: Nguyen, Thanh Thanh L., Liu, Duan, Gao, Huanyao, Ye, Zhenqing, Lee, Jeong‐Heon, Wei, Lixuan, Yu, Jia, Zhang, Lingxin, Wang, Liewei, Ordog, Tamas, Weinshilboum, Richard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652440/
https://www.ncbi.nlm.nih.gov/pubmed/36128656
http://dx.doi.org/10.1111/cts.13402