Cargando…
Glucocorticoids mediate transcriptome‐wide alternative polyadenylation: Potential mechanistic and clinical implications
Alternative polyadenylation (APA) is a common genetic regulatory mechanism that generates distinct 3′ ends for RNA transcripts. Changes in APA have been associated with multiple biological processes and disease phenotypes. However, the role of hormones and their drug analogs in APA remains largely u...
Autores principales: | Nguyen, Thanh Thanh L., Liu, Duan, Gao, Huanyao, Ye, Zhenqing, Lee, Jeong‐Heon, Wei, Lixuan, Yu, Jia, Zhang, Lingxin, Wang, Liewei, Ordog, Tamas, Weinshilboum, Richard M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652440/ https://www.ncbi.nlm.nih.gov/pubmed/36128656 http://dx.doi.org/10.1111/cts.13402 |
Ejemplares similares
-
Glucocorticoids unmask silent non-coding genetic risk variants for common diseases
por: Nguyen, Thanh Thanh L, et al.
Publicado: (2022) -
TCF7L2 lncRNA: a link between bipolar disorder and body mass index through glucocorticoid signaling
por: Liu, Duan, et al.
Publicado: (2021) -
Single Nucleotide Polymorphisms at a Distance from Aryl Hydrocarbon Receptor (AHR) Binding Sites Influence AHR Ligand–Dependent Gene Expression
por: Neavin, Drew R., et al.
Publicado: (2019) -
Pharmacological Targeting of Androgen Receptor Elicits Context-Specific Effects in Estrogen Receptor–Positive Breast Cancer
por: Wei, Lixuan, et al.
Publicado: (2023) -
TREND-DB—a transcriptome-wide atlas of the dynamic landscape of alternative polyadenylation
por: Marini, Federico, et al.
Publicado: (2020)