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Therapeutic Strategies in the Fight against COVID-19: From Bench to Bedside
In December 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in China. This virus rapidly spread worldwide and was declared a global pandemic by the World Health Organization (WHO) in March 2020. High incidence, long incubation period, and diverse clinical signs of the...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Shiraz University of Medical Sciences
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652495/ https://www.ncbi.nlm.nih.gov/pubmed/36380976 http://dx.doi.org/10.30476/IJMS.2021.92662.2396 |
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author | Abadi, Banafshe Aarabi Jeshvaghani, Amir Hossein Fathalipour, Hadis Dehghan, Leili Rahimi Sirjani, Kosar Forootanfar, Hamid |
author_facet | Abadi, Banafshe Aarabi Jeshvaghani, Amir Hossein Fathalipour, Hadis Dehghan, Leili Rahimi Sirjani, Kosar Forootanfar, Hamid |
author_sort | Abadi, Banafshe |
collection | PubMed |
description | In December 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in China. This virus rapidly spread worldwide and was declared a global pandemic by the World Health Organization (WHO) in March 2020. High incidence, long incubation period, and diverse clinical signs of the disease posed a huge challenge globally. The efforts of health systems have been focused on repurposing existing drugs or developing innovative therapies to reduce the morbidity and mortality associated with SARS-CoV-2. In addition, most of the large pharmaceutical companies are intensely working on vaccine development to swiftly deliver safe and effective vaccines to prevent further spread of the virus. In this review, we will discuss the latest data on therapeutic strategies undergoing clinical trials. Additionally, we will provide a summary of vaccines currently under development. |
format | Online Article Text |
id | pubmed-9652495 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Shiraz University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-96524952022-11-14 Therapeutic Strategies in the Fight against COVID-19: From Bench to Bedside Abadi, Banafshe Aarabi Jeshvaghani, Amir Hossein Fathalipour, Hadis Dehghan, Leili Rahimi Sirjani, Kosar Forootanfar, Hamid Iran J Med Sci Review Article In December 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in China. This virus rapidly spread worldwide and was declared a global pandemic by the World Health Organization (WHO) in March 2020. High incidence, long incubation period, and diverse clinical signs of the disease posed a huge challenge globally. The efforts of health systems have been focused on repurposing existing drugs or developing innovative therapies to reduce the morbidity and mortality associated with SARS-CoV-2. In addition, most of the large pharmaceutical companies are intensely working on vaccine development to swiftly deliver safe and effective vaccines to prevent further spread of the virus. In this review, we will discuss the latest data on therapeutic strategies undergoing clinical trials. Additionally, we will provide a summary of vaccines currently under development. Shiraz University of Medical Sciences 2022-11 /pmc/articles/PMC9652495/ /pubmed/36380976 http://dx.doi.org/10.30476/IJMS.2021.92662.2396 Text en Copyright: © Iranian Journal of Medical Sciences https://creativecommons.org/licenses/by-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NoDerivatives 4.0 International License. This license allows reusers to copy and distribute the material in any medium or format in unadapted form only, and only so long as attribution is given to the creator. The license allows for commercial use. |
spellingShingle | Review Article Abadi, Banafshe Aarabi Jeshvaghani, Amir Hossein Fathalipour, Hadis Dehghan, Leili Rahimi Sirjani, Kosar Forootanfar, Hamid Therapeutic Strategies in the Fight against COVID-19: From Bench to Bedside |
title | Therapeutic Strategies in the Fight against COVID-19: From Bench to Bedside |
title_full | Therapeutic Strategies in the Fight against COVID-19: From Bench to Bedside |
title_fullStr | Therapeutic Strategies in the Fight against COVID-19: From Bench to Bedside |
title_full_unstemmed | Therapeutic Strategies in the Fight against COVID-19: From Bench to Bedside |
title_short | Therapeutic Strategies in the Fight against COVID-19: From Bench to Bedside |
title_sort | therapeutic strategies in the fight against covid-19: from bench to bedside |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652495/ https://www.ncbi.nlm.nih.gov/pubmed/36380976 http://dx.doi.org/10.30476/IJMS.2021.92662.2396 |
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