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Outcome and prognostic markers of cirrhotic and non-cirrhotic patients admitted to a hepatology ICU in a tertiary care university hospital

BACKGROUND AND AIM: Patients with decompensated liver cirrhosis are not given priority for ICU admission in the settings of limited place availability. Recently, advances in medical care led to improvement in their survival. Our aim is to study the outcome of patients admitted to our hepatology ICU....

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Autores principales: Abdellatif, Zeinab, Eletreby, Rasha, Samir, Reham, Abdallah, Mohamed, Lithy, Rania, Zayed, Naglaa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Makerere Medical School 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652640/
https://www.ncbi.nlm.nih.gov/pubmed/36407342
http://dx.doi.org/10.4314/ahs.v22i2.43
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author Abdellatif, Zeinab
Eletreby, Rasha
Samir, Reham
Abdallah, Mohamed
Lithy, Rania
Zayed, Naglaa
author_facet Abdellatif, Zeinab
Eletreby, Rasha
Samir, Reham
Abdallah, Mohamed
Lithy, Rania
Zayed, Naglaa
author_sort Abdellatif, Zeinab
collection PubMed
description BACKGROUND AND AIM: Patients with decompensated liver cirrhosis are not given priority for ICU admission in the settings of limited place availability. Recently, advances in medical care led to improvement in their survival. Our aim is to study the outcome of patients admitted to our hepatology ICU. METHODS: We retrieved the data of patients admitted to the Endemic Medicine Department ICU at Kasr Al-Ainy Hospital in the period from November 2014 to May 2018. We included 498 patients who had complete clinical and outcome data in this analysis. The primary outcome was ICU mortality and its predictors. RESULTS: The overall mortality was 48.1% in the liver cirrhosis versus 52.9% in the non-cirrhosis group. The most common presentations of cirrhotic patients were hepatic encephalopathy and hypovolemic shock. The SOFA score and sepsis independently predicted mortality in the overall cohort. CONCLUSION: The mortality of cirrhotic patients admitted to ICU is not higher than non-cirrhotic patients. SOFA score is a good prognostic indicator in patients with cirrhosis.
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spelling pubmed-96526402022-11-18 Outcome and prognostic markers of cirrhotic and non-cirrhotic patients admitted to a hepatology ICU in a tertiary care university hospital Abdellatif, Zeinab Eletreby, Rasha Samir, Reham Abdallah, Mohamed Lithy, Rania Zayed, Naglaa Afr Health Sci Articles BACKGROUND AND AIM: Patients with decompensated liver cirrhosis are not given priority for ICU admission in the settings of limited place availability. Recently, advances in medical care led to improvement in their survival. Our aim is to study the outcome of patients admitted to our hepatology ICU. METHODS: We retrieved the data of patients admitted to the Endemic Medicine Department ICU at Kasr Al-Ainy Hospital in the period from November 2014 to May 2018. We included 498 patients who had complete clinical and outcome data in this analysis. The primary outcome was ICU mortality and its predictors. RESULTS: The overall mortality was 48.1% in the liver cirrhosis versus 52.9% in the non-cirrhosis group. The most common presentations of cirrhotic patients were hepatic encephalopathy and hypovolemic shock. The SOFA score and sepsis independently predicted mortality in the overall cohort. CONCLUSION: The mortality of cirrhotic patients admitted to ICU is not higher than non-cirrhotic patients. SOFA score is a good prognostic indicator in patients with cirrhosis. Makerere Medical School 2022-06 /pmc/articles/PMC9652640/ /pubmed/36407342 http://dx.doi.org/10.4314/ahs.v22i2.43 Text en © 2022 Abdellatif Z et al. https://creativecommons.org/licenses/by/4.0/Licensee African Health Sciences. This is an Open Access article distributed under the terms of the Creative commons Attribution License (https://creativecommons.org/licenses/BY/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Articles
Abdellatif, Zeinab
Eletreby, Rasha
Samir, Reham
Abdallah, Mohamed
Lithy, Rania
Zayed, Naglaa
Outcome and prognostic markers of cirrhotic and non-cirrhotic patients admitted to a hepatology ICU in a tertiary care university hospital
title Outcome and prognostic markers of cirrhotic and non-cirrhotic patients admitted to a hepatology ICU in a tertiary care university hospital
title_full Outcome and prognostic markers of cirrhotic and non-cirrhotic patients admitted to a hepatology ICU in a tertiary care university hospital
title_fullStr Outcome and prognostic markers of cirrhotic and non-cirrhotic patients admitted to a hepatology ICU in a tertiary care university hospital
title_full_unstemmed Outcome and prognostic markers of cirrhotic and non-cirrhotic patients admitted to a hepatology ICU in a tertiary care university hospital
title_short Outcome and prognostic markers of cirrhotic and non-cirrhotic patients admitted to a hepatology ICU in a tertiary care university hospital
title_sort outcome and prognostic markers of cirrhotic and non-cirrhotic patients admitted to a hepatology icu in a tertiary care university hospital
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9652640/
https://www.ncbi.nlm.nih.gov/pubmed/36407342
http://dx.doi.org/10.4314/ahs.v22i2.43
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